MiR-21, miR-34a, miR-125b, miR-181d and miR-648 levels inversely correlate with MGMT and TP53 expression in primary glioblastoma patients

Introduction TP53 and MGMT alterations play a crucial role in glioblastoma (GB) pathogenesis. TP53 and MGMT function is affected by several pathologic mechanisms, such as point mutations or promoter methylation, which are well characterized. Expression of both genes can be regulated by other mechani...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Dorota Jesionek-Kupnicka, Marcin Braun, Berenika Trąbska-Kluch, Joanna Czech, Małgorzata Szybka, Bożena Szymańska, Dominika Kulczycka-Wojdala, Michał Bieńkowski, Radzisław Kordek, Izabela Zawlik
Format:	Artigo
Jezik:	Inglês
Izdano:	Termedia Publishing House 2019-03-01
Serija:	Archives of Medical Science
Teme:	microrna mgmt tp53 o6-methylguanine-dna methyltransferase glioblastoma multiforme (gbm) gb
Online dostop:	https://www.archivesofmedicalscience.com/MiR-21-miR-34a-miR-125b-miR-181d-and-miR-648-levels-inversely-correlate-with-MGMT,69743,0,2.html
Oznake:	Označite Brez oznak, prvi označite!