Trpm2 deficiency in microglia attenuates neuroinflammation during epileptogenesis by upregulating autophagy via the AMPK/mTOR pathway

Epilepsy is one of the most common neurological disorders. Neuroinflammation involving the activation of microglia and astrocytes constitutes an important and common mechanism in epileptogenesis. Transient receptor potential melastatin 2 (TRPM2) is a calcium-permeable, non-selective cation channel t...

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Manylion Llyfryddiaeth

Prif Awduron:	Chen Chen, Tao Zhu, Lifen Gong, Zhe Hu, Hao Wei, Jianchen Fan, Donghui Lin, Xiaojun Wang, Junyu Xu, Xinyan Dong, Yifan Wang, Ningxiao Xia, Linghui Zeng, Peifang Jiang, Yicheng Xie
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2023-10-01
Cyfres:	Neurobiology of Disease
Pynciau:	AMPK/mTOR pathway Astrocytes Autophagy Epileptogenesis Microglia Neuroinflammation
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S0969996123002887
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!