Duplication of 8q24 in Chronic Lymphocytic Leukemia: Cytogenetic and Molecular Biologic Analysis of MYC Aberrations

Chronic lymphocytic leukemia (CLL) with cytogenetics findings, such as complex karyotype and deletions of TP53 or ATM, is associated with adverse clinical outcomes. Additional chromosomal abnormalities further stratify patients into groups with diverse prognoses. Gain of 8q24 is one of the abnormali...

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Detalhes bibliográficos

Principais autores:	Eva Ondroušková, Michaela Bohúnová, Kristýna Závacká, Patrik Čech, Petra Šmuhařová, Miroslav Boudný, Martina Oršulová, Anna Panovská, Lenka Radová, Michael Doubek, Karla Plevová, Marie Jarošová
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-06-01
coleção:	Frontiers in Oncology
Assuntos:	chronic lymphocytic leukemia MYC complex karyotype 8q24 gain prognosis
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fonc.2022.859618/full
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