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Transcriptional Control of Subcutaneous Adipose Tissue by the Transcription Factor CTCF Modulates Heterogeneity in Fat Distribution in Women

Determining the mechanism driving body fat distribution will provide insights into obesity-related health risks. We used functional genomics tools to profile the epigenomic landscape to help infer the differential transcriptional potential of apple- and pear-shaped women’s subcutaneous adipose-deriv...

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Principais autores: Edina Erdos, Katalin Sandor, Crystal L. Young-Erdos, Laszlo Halasz, Steven R. Smith, Timothy F. Osborne, Adeline Divoux
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-12-01
Serier:Cells
Fag:
fat distribution
adipose-derived stem cells
CTCF
RNAPII
bivalent chromatin
epigenetic
Online adgang:https://www.mdpi.com/2073-4409/13/1/86
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