Clinical implications of serum neurofilament in newly diagnosed MS patients: A longitudinal multicentre cohort study

Background: We aim to evaluate serum neurofilament light chain (sNfL), indicating neuroaxonal damage, as a biomarker at diagnosis in a large cohort of early multiple sclerosis (MS) patients. Methods: In a multicentre prospective longitudinal observational cohort, patients with newly diagnosed relaps...

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Autori principali:	Stefan Bittner, Falk Steffen, Timo Uphaus, Muthuraman Muthuraman, Vinzenz Fleischer, Anke Salmen, Felix Luessi, Achim Berthele, Luisa Klotz, Sven G. Meuth, Antonios Bayas, Friedemann Paul, Hans-Peter Hartung, Ralf Linker, Christoph Heesen, Martin Stangel, Brigitte Wildemann, Florian Then Bergh, Björn Tackenberg, Tania Kuempfel, Frank Weber, Uwe K. Zettl, Ulf Ziemann, Hayrettin Tumani, Sergiu Groppa, Mark Mühlau, Carsten Lukas, Bernhard Hemmer, Heinz Wiendl, Ralf Gold, Frauke Zipp
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2020-06-01
Serie:	EBioMedicine
Soggetti:	Neurofilament light chain sNfL Multiple sclerosis Prediction Biomarker
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2352396420301821
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