Differential conformational expansion of NUP98-HOXA9 oncoprotein from nanosized assemblies to macrophases
Abstract Transcription factors (TFs) play a central role in gene regulation by binding to specific DNA sequences and orchestrating the transcriptional machinery. A majority of eukaryotic TFs have a block copolymer architecture, with at least one block being a folded DNA interaction domain, and anoth...
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| Principais autores: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2025-11-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-025-66327-1 |
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