The association of enlarged perivascular space with microglia-related inflammation and Alzheimer's pathology in cognitively normal elderly

Background: Glymphatic dysfunction may contribute to the accumulation of Alzheimer's disease (AD) pathologies. Conversely, AD pathologic change might also cause neuroinflammation and aggravate glymphatic dysfunction, forming a loop that accelerates AD progression. In vivo validations are needed to c...

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Detalhes bibliográficos

Principais autores:	Qingze Zeng, Kaicheng Li, Xiao Luo, Shuyue Wang, Xiaopei Xu, Yeerfan Jiaerken, Xiaocao Liu, Luwei Hong, Hui Hong, Zheyu Li, Yanv Fu, Tianyi Zhang, Yanxing Chen, Zhirong Liu, Peiyu Huang, Minming Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2022-08-01
coleção:	Neurobiology of Disease
Assuntos:	Perivascular space Alzheimer's disease Neuroinflammation Amyloid Tau Microglial activation
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S0969996122001474
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