Epigallocatechin gallate ameliorates brain injuries after intracerebral hemorrhage by inhibiting ferroptosis through upregulation of Nrf2-Keap1 pathway

Intracerebral hemorrhage (ICH) has high mortality and disability with limited efficient therapies. The inhibition of ferroptosis is implicated in the prognosis of ICH. Epigallocatechin gallate (EGCG) has iron chelating, anti-inflammatory and free radical scavenging properties, which connected with N...

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Autori principali:	Sheng-Yu Zhou, Zhen-Ni Guo, Ying-Ying Sun, Wen-Bo Jia, Hong-Jing Zhu, Jie Liu, Yang Qu, Hang Jin
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2026-04-01
Serie:	Brain Research Bulletin
Soggetti:	Intracerebral hemorrhage Epigallocatechin gallate Ferroptosis Iron metabolism Nrf2-Keap1 pathway
Accesso online:	http://www.sciencedirect.com/science/article/pii/S0361923026000985
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