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Genome profiling of <it>ERBB2</it>-amplified breast cancers

<p>Abstract</p> <p>Background</p> <p>Around 20% of breast cancers (BC) show <it>ERBB2 </it>gene amplification and overexpression of the ERBB2 tyrosine kinase receptor. They are associated with a poor prognosis but can benefit from targeted therapy. A better knowledge of these BCs, genomically and bi...

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Principais autores: Ayed Farhat, Tarpin Carole, Charafe-Jauffret Emmanuelle, Innocenti Charlène, Raynaud Stéphane, Bonansea Julien, Hamida Azza, Adélaïde José, Finetti Pascal, Bekhouche Ismahane, Sircoulomb Fabrice, Viens Patrice, Jacquemier Jocelyne, Bertucci François, Birnbaum Daniel, Chaffanet Max
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2010-10-01
Serier:BMC Cancer
Online adgang:http://www.biomedcentral.com/1471-2407/10/539
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