Long-term feeding of high-fat plus high-fructose diet induces isolated impaired glucose tolerance and skeletal muscle insulin resistance in miniature pigs

Abstract Background During the prediabetic development, the changes in β-cell function and tissue-specific insulin resistance have been described. However, there are conflicting views in insulin secretory capacity between early clinical observation and recent proposed mathematical model. On the basi...

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Principais autores:	Meng-Chieh Hsu, Mu-En Wang, Yi-Fan Jiang, Hung-Chang Liu, Yi-Chen Chen, Chih-Hsien Chiu
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2017-10-01
Serija:	Diabetology & Metabolic Syndrome
Teme:	Insulin resistance Miniature pig High fat high fructose diet IVGTT Impaired glucose tolerance
Online dostop:	http://link.springer.com/article/10.1186/s13098-017-0281-6
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