Gestational intermittent hypoxia reduces mandibular growth with decreased Sox9 expression and increased Hif1a expression in male offspring rats

IntroductionMaternal obstructive sleep apnea (OSA) during pregnancy is the risk factor for impaired fetal growth with low birth weight in the offspring. However, it is unclear whether gestational intermittent hypoxia (IH, a hallmark of maternal OSA) has long-term detrimental consequences on the skel...

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Bibliografiset tiedot

Päätekijät:	Takumi Suzuki, Jun Hosomichi, Hideyuki Maeda, Yuji Ishida, Risa Usumi-Fujita, Manaka Moro, Korkuan Jariyatheerawong, Takashi Ono
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Frontiers Media S.A. 2024-06-01
Sarja:	Frontiers in Physiology
Aiheet:	obstructive sleep apnea intermittent hypoxia pregnant DOHAD skeletal growth SOX9
Linkit:	https://www.frontiersin.org/articles/10.3389/fphys.2024.1397262/full
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