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Prognosis and oncogenomic profiling of patients with tropomyosin receptor kinase fusion cancer in the 100,000 genomes project

Introduction: Neurotrophic tyrosine receptor kinase (NTRK) gene fusions are oncogenic drivers in various tumor types. Limited data exist on the overall survival (OS) of patients with tumors with NTRK gene fusions and on the co-occurrence of NTRK fusions with other oncogenic drivers. Materials and Me...

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Principais autores: John Bridgewater, Xiaolong Jiao, Mounika Parimi, Clare Flach, Jeran Stratford, Atanas Kamburov, Arndt A. Schmitz, Jihong Zong, John A. Reeves, Karen Keating, Amanda Bruno, Marc Fellous, Mariana Buongermino Pereira, Lyudmila Bazhenova
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2022-01-01
Serier:Cancer Treatment and Research Communications
Fag:
NTRK
TRK
Gene fusion
Genomic profiling
Real world evidence
Online adgang:http://www.sciencedirect.com/science/article/pii/S2468294222001149
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