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Next-generation cell lines for profiling different proteasome forms and their implications in cancer

BackgroundMost intracellular proteins undergo degradation by proteasomes, which exist in constitutive, immune, and intermediate forms. The diversity arises from the presence of different catalytic β subunits incorporated into the 20S core particle. Constitutive proteasomes contain β1, β2 and β5 subu...

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Bibliografiske detaljer
Principais autores: Alexander Burov, Anastasia Yakovleva, Georgy Linovskiy, Andrei Fedotov, Vladimir Popenko, Olga Leonova, Aleksandr Lanin, Marina Drutskaya, Vadim Karpov, Alexey Morozov
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-12-01
Serier:Frontiers in Immunology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1672000/full
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