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Restrained glycoprotein VI-induced platelet signaling by tyrosine protein phosphatases independent of phospholipase Cγ2

The platelet collagen receptor glycoprotein VI (GPVI) signals to activation of phospholipase Cγ2 (PLCγ2) and phosphoinositide 3-kinases (PI3K), causing platelet activation and aggregation. The non-receptor Src homology tyrosine phosphatases Shp1/2 modulate GPVI signaling in partly opposite ways, bo...

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Príomhchruthaitheoirí: Jingnan Huang, Delia I. Fernández, Jinmi Zou, Xueqing Wang, Johan W.M. Heemskerk, Ángel García
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: PAGEPress Publications 2023-10-01
Sraith:Bleeding, Thrombosis and Vascular Biology
Ábhair:
Rochtain ar líne:https://btvb.org/btvb/article/view/93
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