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Characterization of two multidrug-resistant Klebsiella pneumoniae harboring tigecycline-resistant gene tet(X4) in China

ObjectivesTigecycline is recognized as one of the last-line antibiotics to treat serious bacterial infection caused by carbapenem-resistant Klebsiella pneumoniae (CRKP). The plasmid-borne gene tet(X4) mediates high resistance to tigecycline. However, the prevalence and genetic context of tet(X4) in...

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Principais autores: Yanxian Yang, Ruowen He, Yiping Wu, Mingyang Qin, Jieyun Chen, Yu Feng, Runping Zhao, Lei Xu, Xilong Guo, Guo-Bao Tian, Min Dai, Bin Yan, Li-Na Qin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2023-04-01
coleção:Frontiers in Microbiology
Assuntos:
Klebsiella pneumoniae
tigecycline resistance
tet(X4)
horizontal transfer
swine
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1130708/full
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