Lysate of Parabacteroides distasonis prevents severe forms of experimental autoimmune encephalomyelitis by modulating the priming of T cell response

The gut microbiota influences the reactivity of the immune system, and Parabacteroides distasonis has emerged as an anti-inflammatory commensal. Here, we investigated whether its lysate could prevent severe forms of neuroinflammation in experimental autoimmune encephalomyelitis (EAE) in mice and how...

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Hauptverfasser:	Zuzana Jiraskova Zakostelska, Michal Kraus, Stepan Coufal, Petra Prochazkova, Zaneta Slavickova, Tomas Thon, Tomas Hrncir, Jakub Kreisinger, Klara Kostovcikova, Pavlina Kleinova, Jana Lizrova Preiningerova, Miluse Pavelcova, Veronika Ticha, Ivana Kovarova, Eva Kubala Havrdova, Helena Tlaskalova-Hogenova, Miloslav Kverka
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2024-12-01
Schriftenreihe:	Frontiers in Immunology
Schlagworte:	multiple sclerosis experimental autoimmune encephalomyelitis inflammation Parabacteroides distasonis microbiota regulatory T cells
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1475126/full
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