Código QR (código de barras bidimensional)

A novel USP4 inhibitor that suppresses colorectal cancer stemness by promoting β-catenin and Twist1 degradation

Abstract Background The high mortality rate of metastatic colorectal cancer (CRC) is primarily attributed to resistance to chemotherapy, where cancer stem cells (CSCs) play a crucial role. Deubiquitinating enzymes are essential regulators of CSC maintenance, making them potential targets for elimina...

Fuld beskrivelse

Na minha lista:
Principais autores: Fengtian Li, Yi Zhou, Xinyue Lin, Yaxin Zhang, Qingyong Hu, Enen Zhao, Huali Li, Xingyan Pan, Feng Shu, Kun Zhang, Chengmei Huang, Na Tang, Wenting Liao
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-01-01
Serier:Journal of Translational Medicine
Fag:
USP4
Chemotherapy resistance
Cancer stem cells
β-catenin
Twist1
Small molecule inhibitor
Online adgang:https://doi.org/10.1186/s12967-024-06001-0
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker