Disturbing Cholesterol/Sphingolipid Metabolism by Squalene Epoxidase Arises Crizotinib Hepatotoxicity
Abstract Metabolic disorders have been identified as one of the causes of drug‐induced liver injury; however, the direct regulatory mechanism regarding this disorder has not yet been clarified. In this study, a single regulatory mechanism of small molecule kinase inhibitors, with crizotinib as the r...
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| Autori principali: | , , , , , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Wiley
2025-04-01
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| Serie: | Advanced Science |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1002/advs.202414923 |
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