Elevated circulating cell-free mitochondrial DNA in fabry disease: insights into inflammatory activation

ObjectiveThis study aimed to investigate mitochondrial dysfunction and its role in the pathogenesis of Fabry disease (FD) by analyzing circulating cell-free DNA (ccf-DNA) in patients with FD.MethodsSixty-six FD patients and 21 healthy controls (ctrls) were enrolled. Levels of plasma mitochondrial- (...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Yujing Yuan, Xinyu Zhang, Yawen Zhao, Yikang Wang, Jingyi Huang, Qingqing Wang, Xueqin Song, Jianwen Deng, Zhaoxia Wang, Yun Yuan, Wei Zhang
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2026-01-01
Serie:	Frontiers in Immunology
Soggetti:	ccf-mtDNA enzyme replacement therapy Fabry disease inflammatory cytokines mitochondrial dysfunction
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1706045/full
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!