TGFβ1-induced hedgehog signaling suppresses the immune response of brain microvascular endothelial cells elicited by meningitic Escherichia coli

Abstract Background Meningitic Escherichia coli (E. coli) is the major etiological agent of bacterial meningitis, a life-threatening infectious disease with severe neurological sequelae and high mortality. The major cause of central nervous system (CNS) damage and sequelae is the bacterial-induced i...

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Главные авторы:	Jinrui Sun, Ruicheng Yang, Jiyang Fu, Dong Huo, Xinyi Qu, Chen Tan, Huanchun Chen, Xiangru Wang
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2024-02-01
Серии:	Cell Communication and Signaling
Предметы:	TGFβ1 Hedgehog signaling SAG Brain microvascular endothelial cells miR-155 Neuroinflammation
Online-ссылка:	https://doi.org/10.1186/s12964-023-01383-y
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