The Interactions of Anti-HIV Pronucleotides with a Model Phospholipid Membrane

Pronucleotides, after entering the cell, undergo chemical or enzymatic conversion into nucleotides with a free phosphate residue, and the released nucleoside 5′-monophosphate is then phosphorylated to the biologically active form, namely nucleoside 5′-triphosphate. The active form can inhibit HIV vi...

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Principais autores:	Monika Rojewska, Joanna Romanowska, Adam Kraszewski, Michał Sobkowski, Krystyna Prochaska
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2024-12-01
Serija:	Molecules
Teme:	anti-HIV pronuclotides azidothymidine derivatives DPPC Langmuir monolayer π–A isotherms relaxation of the phospholipid film
Online dostop:	https://www.mdpi.com/1420-3049/29/23/5787
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