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Modification of adipose mass by targeting distal enhancers of Ptrf

Abstract Background Adipose tissue plays a central role in systemically metabolic regulation. Polymerase I and transcript release factor (PTRF) is responsible for caveolae structure formation and plays a crucial role in lipid metabolism. Results We investigated the possibility of modifying adipose m...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Yu Zhang, Keren Long, Songling Zhang, Biwei Zhang, Xiaokai Li, Xuemin Li, Zhining Zhong, Ziqi Li, Qiuyue Chen, Penghao Li, Li Chen, Jinwei Zhang, Jianlin Yuan, Anan Jiang, Lu Lu, Haohuan Li, Long Jin, Liangpeng Ge, Peng Shang, Xuewei Li, Mingzhou Li
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2025-09-01
Rangatū:BMC Biology
Ngā marau:
Ptrf
SnRNA-seq
Chromatin interaction
4C-seq
Enhancer
Urunga tuihono:https://doi.org/10.1186/s12915-025-02405-6
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