An In Vitro Calibration Model for Vancomycin Quantification in Brain Extracellular Fluid: Toward Improved Dosing in Postoperative Infections

ABSTRACT Postoperative central nervous system (CNS) infections are associated with high mortality and present a therapeutic challenge due to limited antibiotic penetration into the brain extracellular fluid (ECF). Vancomycin, frequently used in this setting, requires therapeutic drug monitoring; how...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Skaistė Žukaitienė, Ainė Žygaitė, Gabrielė Milkintaitė, Jolita Pancerė, Neringa Balčiūnienė, Astra Vitkauskienė, Romaldas Mačiulaitis
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Wiley 2025-10-01
Цуврал:	Pharmacology Research & Perspectives
Нөхцлүүд:	calibration central nervous system infections microdialysis pharmacokinetics vancomycin
Онлайн хандалт:	https://doi.org/10.1002/prp2.70179
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!