USP14 maintains HIF1-α stabilization via its deubiquitination activity in hepatocellular carcinoma

Abstract Hepatocellular carcinoma (HCC) is the most common visceral neoplasms with its heterogeneity and high rate of recurrence. HCC is characterized to be delayed diagnosis and the development of resistant disease. However, the molecular mechanism for HCC pathogenesis and progression remains large...

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Detalhes bibliográficos

Principais autores:	Chi Lv, Shengli Wang, Lin Lin, Chunyu Wang, Kai Zeng, Yiming Meng, Ge Sun, Shan Wei, Yefu Liu, Yue Zhao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2021-08-01
coleção:	Cell Death and Disease
Acesso em linha:	https://doi.org/10.1038/s41419-021-04089-6
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