Recapitulation of physiologic and pathophysiologic pulsatile CSF flow in purpose-built high-throughput hydrocephalus bioreactors

Abstract Background Hydrocephalus, an accumulation of cerebrospinal fluid (CSF) in the ventricles of the brain, is often treated via a shunt system to divert the excess CSF to a different compartment; if left untreated, it can lead to serious complications and permanent brain damage. It is estimated...

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Hauptverfasser:	Ahmad Faryami, Adam Menkara, Shaheer Ajaz, Christopher Roberts, Ryan Jaroudi, Blake Gura, Tala Hussini, Carolyn A. Harris
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-12-01
Schriftenreihe:	Fluids and Barriers of the CNS
Schlagworte:	Hydrocephalus In vitro modeling Cerebrospinal fluid flow pattern CSF dynamics Microfluidic Pump
Online-Zugang:	https://doi.org/10.1186/s12987-024-00600-1
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