Hyper-phosphorylation of Rb S249 together with CDK5R2/p39 overexpression are associated with impaired cell adhesion and epithelial-to-mesenchymal transition: Implications as a potential lung cancer grading and staging biomarker.

Prediction of lung cancer metastasis relies on post-resection assessment of tumor histology, which is a severe limitation since only a minority of lung cancer patients are diagnosed with resectable disease. Therefore, characterization of metastasis-predicting biomarkers in pre-resection small biopsy...

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Huvudupphov:	Jaileene Pérez-Morales, Darielys Mejías-Morales, Stephanie Rivera-Rivera, Jonathan González-Flores, Mónica González-Loperena, Fernando Y Cordero-Báez, Wilfredo M Pedreira-García, Camille Chardón-Colón, Jennifer Cabán-Rivera, W Douglas Cress, Edna R Gordian, Teresita Muñoz-Antonia, Mauricio Cabrera-Ríos, Angel Isidro, Domenico Coppola, Marilin Rosa, Theresa A Boyle, Victoria Izumi, John M Koomen, Pedro G Santiago-Cardona
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Public Library of Science (PLoS) 2018-01-01
Serie:	PLoS ONE
Länkar:	http://europepmc.org/articles/PMC6242691?pdf=render
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