Polygoni Multiflori Radix Improves Dyslipidemia by Regulating Hepatocyte Lipid Metabolism Mediated via the AMPK/SREBP-2/PCSK9/LDLR Signaling Pathway

Objective: To clarify the molecular mechanism of Polygoni Multiflori Radix in improving dyslipidemia and provide a scientific basis for its clinical application. Methods: Network pharmacology, molecular docking and simulation were used to predict and verify active components and core targets of Poly...

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Bibliografische Detailangaben

Hauptverfasser:	Tongye Wang, Lijuan Zhang, Yue Wang, Jianguo Xing, Lei Xu, Xu Hu, Wenling Su, Ruifang Zheng
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2026-03-01
Schriftenreihe:	Metabolites
Schlagworte:	<i>Polygonum multiflorum</i> AMPK SREBP-2 PCSK9 LDLR signaling pathway
Online-Zugang:	https://www.mdpi.com/2218-1989/16/4/230
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