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A study of Smad4, Smad6 and Smad7 in Surgically Resected Samples of Pancreatic Ductal Adenocarcinoma and Their Correlation with Clinicopathological Parameters and Patient Survival

<p>Abstract</p> <p>Background</p> <p>Smad4 is the common mediator of the tumor suppressive functions of TGF-beta. Smad6 and Smad7 are the antagonists of the TGF-beta pathway. This study investigates the differential protein expressions of Smad4, Smad6 and Smad7 in tumor as compared to normal tissue...

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Principais autores: Singh Puneet, Srinivasan Radhika, Wig Jai, Radotra Bishan
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2011-12-01
Series:BMC Research Notes
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Acceso en liña:http://www.biomedcentral.com/1756-0500/4/560
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