Peripheral immune and kynurenine profiles are associated with cognitive change during early treatment of first-episode schizophrenia

ObjectiveTo delineate the longitudinal relationships among peripheral inflammation, kynurenine pathway (KP) dysregulation, immune-cell redistribution, and cognitive performance in antipsychotic-naïve first-episode schizophrenia (FES).MethodsAntipsychotic-naïve FES patients (n = 136) and healthy cont...

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Detalhes bibliográficos

Principais autores:	Jin-lei Tang, Fan-Fan Xu, Lian Wu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-03-01
Colecção:	Frontiers in Psychiatry
Assuntos:	cognition first-episode schizophrenia inflammation kynurenine pathway monocytes
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fpsyt.2026.1791018/full
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