Tanshinone IIA reduces tubulointerstitial fibrosis by suppressing GSDMD-mediated pyroptosis

Context Tanshinone IIA (Tan IIA), a bioactive compound derived from the traditional Chinese herb Salvia miltiorrhiza (Family Lamiaceae, Authority Bunge), is well-known for its protective effects in various kidney diseases. However, its role in obstructive nephropathy has not been thoroughly investig...

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Hauptverfasser:	Xueling Yang, Qinglin Luo, Zhifen Wu, Chunxuan Wang, Yuanjing Yang, Luquan Zheng, Ke Li, Lei Zhao, Yang Jurong
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis Group 2025-12-01
Schriftenreihe:	Pharmaceutical Biology
Schlagworte:	Chinese herbal medicine unilateral ureteral obstruction cell death chronic kidney disease Gasdermin D pyroptosis
Online-Zugang:	https://www.tandfonline.com/doi/10.1080/13880209.2025.2498166
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