Improvement of the Targeting of Radiolabeled and Functionalized Liposomes with a Two-Step System Using a Bispecific Monoclonal Antibody (Anti-CEA × Anti-DTPA–In)

This study proposes liposomes as a new tool for pretargeted radioimmunotherapy (RIT) in solid tumors. Tumor pretargeting is obtained by using a bispecific monoclonal antibody (BsmAb, anti-CEA x anti-DTPA-In) and pegylated radioactive liposomes containing a lipid-hapten conjugate (DSPE-PEG-DTPA-In)....

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Aurore eRauscher, Mathieu eFrindel, Holisoa eRajérison, Sébastien eGouard, Catherine eMaurel, Jacques eBarbet, Alain eFaivre-Chauvet, Marie eMougin-Degraef
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Frontiers Media S.A. 2015-11-01
سلاسل:	Frontiers in Medicine
الموضوعات:	Radioimmunotherapy solid tumors pretargeting bispecific antibody PEGylated liposomes
الوصول للمادة أونلاين:	http://journal.frontiersin.org/Journal/10.3389/fmed.2015.00083/full
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

Improvement of the Targeting of Radiolabeled and Functionalized Liposomes with a Two-Step System Using a Bispecific Monoclonal Antibody (Anti-CEA &#215; Anti-DTPA–In)

مواد مشابهة

Improvement of the Targeting of Radiolabeled and Functionalized Liposomes with a Two-Step System Using a Bispecific Monoclonal Antibody (Anti-CEA × Anti-DTPA–In)