Proteasomal Degradation of Mutant Huntingtin Exon1 Regulates Autophagy
Accumulation of misfolded proteins is implicated in neurodegenerative diseases. One of these is Huntington’s disease, which is caused by an expansion of trinucleotide (CAG) repeats in exon 1 of huntingtin gene (<i>HTT</i>). This expansion results in the production of mutant huntingtin exon1 protein...
Tallennettuna:
| Päätekijät: | , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
MDPI AG
2025-12-01
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| Sarja: | Cells |
| Aiheet: | |
| Linkit: | https://www.mdpi.com/2073-4409/15/1/68 |
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