Synthesis of long-chain polyunsaturated fatty acids in lactating mammary gland: role of Δ5 and Δ6 desaturases, SREBP-1, PPARα, and PGC-1

The purpose of this work was to study whether rat lactating mammary gland can synthesize PUFAs through the expression of Δ5 and Δ6 desaturases (Δ5D and Δ6D), whether these enzymes are regulated by the transcription factors sterol-regulatory element binding protein 1 (SREBP-1) and peroxisome prolifer...

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Autori principali:	Maricela Rodriguez-Cruz, Armando R. Tovar, Berenice Palacios-GonzaÌlez, Martha del Prado, Nimbe Torres
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2006-03-01
Serie:	Journal of Lipid Research
Soggetti:	sterol-regulatory element binding protein 1 peroxisome proliferator-activated receptor α peroxisome proliferator-activated receptor γ coactivator 1
Accesso online:	http://www.sciencedirect.com/science/article/pii/S0022227520336099
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