Refining letermovir prophylaxis strategies and CD4 + T cell-guided discontinuation in aplastic anemia patients post-allogeneic HSCT: a retrospective analysis

Abstract Introduction Cytomegalovirus (CMV) infection is a significant complication in aplastic anemia (AA) patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT). While letermovir has shown efficacy in CMV prophylaxis, the optimal timing for discontinuing letermovir rema...

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Principais autores:	Yuling Zhang, Xiaoqing He, Ming Zhou, Yuping Zhang, Wenjian Mo, Ruiqing Zhou, Yumiao Li, Qi Xiang, Fangfang Yang, Shilin Xu, Caixia Wang, Wei Zhou, Tingfen Deng, Shiyi Pan, LiangLiang Wu, Shunqing Wang, Xiaowei Chen
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2026-01-01
Series:	European Journal of Medical Research
Assuntos:	Letermovir Aplastic anemia Allogeneic hematopoietic stem cell transplantation Cytomegalovirus infections
Acceso en liña:	https://doi.org/10.1186/s40001-025-03794-8
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