IL-17A and IFN-γ synergistically induce RNase 7 expression via STAT3 in primary keratinocytes.

Human keratinocytes produce several antimicrobial peptides and proteins (AMP) which contribute to the protection of human skin against infection. RNase 7 is a major AMP involved in cutaneous defense with a high expression in keratinocytes and a broad spectrum of antimicrobial activity. The cytokine...

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Hlavní autoři:	Maren Simanski, Franziska Rademacher, Lena Schröder, Hanna Maria Schumacher, Regine Gläser, Jürgen Harder
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Public Library of Science (PLoS) 2013-01-01
Edice:	PLoS ONE
On-line přístup:	http://europepmc.org/articles/PMC3605401?pdf=render
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