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Combining Subtractive Genomics with Computer-Aided Drug Discovery Techniques to Effectively Target <i>S. sputigena</i> in Periodontitis

This study aimed to provide an inclusive in silico investigation for the identification of novel drug targets that can be exploited to develop drug candidates for treating oral infections caused by <i>S. sputigena</i>. By coupling subtractive genomics with an in silico drug discovery approach, we id...

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Asıl Yazarlar: Mallari Praveen, Chendruru Geya Sree, Simone Brogi, Vincenzo Calderone, Kamakshya Prasad Kanchan Prava Dalei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2025-02-01
Seri Bilgileri:Computation
Konular:
<i>S. sputigena</i>
drug targets
cubebin
in silico drug discovery
dTDP-4-dehydrorhamnose-3,5-epimerase
UTP-glucose-1-phosphate uridylytransferase
Online Erişim:https://www.mdpi.com/2079-3197/13/2/34
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