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Methionine synthase A2756G and reduced folate carrier1 A80G gene polymorphisms as maternal risk factors for Down syndrome in Egypt

Background: Polymorphisms of genes encoding enzymes involved in folate metabolism have long been hypothesized to be maternal risk factors for Down syndrome, however, results are conflicting and inconclusive. Aim of the study: To analyze the effect of methionine synthase (MTR) A2756G, and reduced fol...

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Principais autores: Maha Moustafa, Elham Gaber, Gamal Abo El Fath
Formato: Artigo
Idioma:Inglês
Publicado em: SpringerOpen 2016-04-01
coleção:Egyptian Journal of Medical Human Genetics
Assuntos:
Down syndrome
Methionine synthase
Reduced folate carrier
Gene polymorphism
Maternal risk
Egypt
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S1110863015001135
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