Dexamethasone attenuates interferon-related cytokine hyperresponsiveness in COVID-19 patients

BackgroundDexamethasone improves the survival of COVID-19 patients in need of supplemental oxygen therapy. Although its broad immunosuppressive effects are well-described, the immunological mechanisms modulated by dexamethasone in patients hospitalized with COVID-19 remain to be elucidated.Objective...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Job J. Engel, Caspar I. van der Made, Nick Keur, Todia Setiabudiawan, Rutger J. Röring, Georgia Damoraki, Helga Dijkstra, Heidi Lemmers, Sofia Ioannou, Garyfallia Poulakou, Jos W. M. van der Meer, Evangelos J. Giamarellos-Bourboulis, Vinod Kumar, Frank L. van de Veerdonk, Mihai G. Netea, Athanasios Ziogas
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2023-08-01
Edice:	Frontiers in Immunology
Témata:	COVID-19 SARS-CoV-2 dexamethasone cytokine storm interferon ISG15
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1233318/full
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!