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JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling

Morphogens regulate growth and pattern in vertebrate and invertebrate limbs. Here, the authors show that the JAK/STAT pathway promotes the growth of the Hedgehog-producing cell population in theDrosophilawing, thereby allowing the stable localization of the BMP/Dpp organizer.

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Bibliografiske detaljer
Principais autores: Carles Recasens-Alvarez, Ana Ferreira, Marco Milán
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2017-01-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/ncomms13815
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