Engineering Saccharomyces cerevisiae for the production and secretion of Affibody molecules

Abstract Background Affibody molecules are synthetic peptides with a variety of therapeutic and diagnostic applications. To date, Affibody molecules have mainly been produced by the bacterial production host Escherichia coli. There is an interest in exploring alternative production hosts to identify...

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Autors principals:	Veronica Gast, Anna Sandegren, Finn Dunås, Siri Ekblad, Rezan Güler, Staffan Thorén, Marta Tous Mohedano, Mikael Molin, Martin K. M. Engqvist, Verena Siewers
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2022-03-01
Col·lecció:	Microbial Cell Factories
Matèries:	Recombinant protein production Heterologous protein production Secretion Proteases Pep4 Prc1
Accés en línia:	https://doi.org/10.1186/s12934-022-01761-0
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