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Summary of single nucleotide polymorphisms in filaggrin associated with atopic dermatitis

Abstract Background Loss of function mutations in the filaggrin gene (FLG) play an important role in the pathogenesis of atopic dermatitis (AD). However, FLG is structurally challenging to sequence using conventional high‐throughput techniques. Genome‐wide association studies (GWAS) chips and imputa...

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Main Authors: Rachita Pandya, Mohsen Baghchechi, Sinead Langan, David J. Margolis, Lavinia Paternoster, Cathryn Sibbald, Joy Wan, Saman Zaman, Katrina Abuabara
Format: Artigo
Language:Inglês
Published: Wiley 2024-06-01
Series:JEADV Clinical Practice
Subjects:
atopic dermatitis
eczema
epidemiology
filaggrin
single‐nucleotide polymorphism
Online Access:https://doi.org/10.1002/jvc2.330
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