GSDMD-mediated pyroptosis dominantly promotes left ventricular remodeling and dysfunction in post-myocardial infarction: a comparison across modes of programmed cell death and mitochondrial involvement

Abstract Background Myocardial infarction (MI) has recently accounted for more than one-third of global mortality. Multiple molecular pathological pathways, such as oxidative stress, inflammation, and mitochondrial dysfunction, have been recognized as possible mechanisms in the development of MI. Fu...

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Κύριοι συγγραφείς:	Chanon Piamsiri, Chayodom Maneechote, Kewarin Jinawong, Busarin Arunsak, Titikorn Chunchai, Wichwara Nawara, Siriporn C Chattipakorn, Nipon Chattipakorn
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	BMC 2023-01-01
Σειρά:	Journal of Translational Medicine
Θέματα:	Myocardial infarction Heart failure Programmed cell death Pyroptosis Mitochondria
Διαθέσιμο Online:	https://doi.org/10.1186/s12967-023-03873-6
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