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Early detection of opioid-induced constipation in patients initiating weak opioids for chronic non-cancer pain

Abstract This post hoc analysis of a Japanese cohort study aimed to identify factors that could assist in early prediction of opioid-induced constipation (OIC). The onset of OIC and the predictive accuracy (sensitivity, specificity, likelihood ratios, and positive predictive values) of early constip...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Yasuhide Morioka, Akira Hashimoto, Yuichi Koretaka, Shihomi Wada, Motoki Sonohata, Asbjørn Mohr Drewes
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2026-03-01
Rangatū:Scientific Reports
Ngā marau:
Non-cancer pain
Opioid-induced constipation
Positive likelihood ratio
Posterior probabilities
Rome IV diagnostic criteria
Weak opioids
Urunga tuihono:https://doi.org/10.1038/s41598-026-45169-x
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