Bruton’s tyrosine kinase-bearing B cells and microglia in neuromyelitis optica spectrum disorder

Abstract Background Neuromyelitis optica spectrum disorder (NMOSD) is an inflammatory autoimmune disease of the central nervous system that involves B-cell receptor signaling as well as astrocyte–microglia interaction, which both contribute to evolution of NMOSD lesions. Main body Through transcript...

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Principais autores:	Ye Liu, Zhenning Huang, Tian-Xiang Zhang, Bin Han, Guili Yang, Dongmei Jia, Li Yang, Qiang Liu, Alexander Y. L. Lau, Friedemann Paul, Alexei Verkhratsky, Fu-Dong Shi, Chao Zhang
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2023-12-01
Series:	Journal of Neuroinflammation
Assuntos:	Neuromyelitis optica spectrum disorder B cells Microglia Bruton’s tyrosine kinase Zanubrutinib
Acceso en liña:	https://doi.org/10.1186/s12974-023-02997-2
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