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Helicobacter pylori perturbs iron trafficking in the epithelium to grow on the cell surface.

Helicobacter pylori (Hp) injects the CagA effector protein into host epithelial cells and induces growth factor-like signaling, perturbs cell-cell junctions, and alters host cell polarity. This enables Hp to grow as microcolonies adhered to the host cell surface even in conditions that do not suppor...

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Detalles Bibliográficos
Autores principales: Shumin Tan, Jennifer M Noto, Judith Romero-Gallo, Richard M Peek, Manuel R Amieva
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2011-05-01
Colección:PLoS Pathogens
Acceso en línea:http://europepmc.org/articles/PMC3093365?pdf=render
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