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Therapeutic Effects of Procainamide on Endotoxin-Induced Rhabdomyolysis in Rats.

Overt systemic inflammatory response is a predisposing mechanism for infection-induced skeletal muscle damage and rhabdomyolysis. Aberrant DNA methylation plays a crucial role in the pathophysiology of excessive inflammatory response. The antiarrhythmic drug procainamide is a non-nucleoside inhibito...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Chih-Chin Shih, Hiong-Ping Hii, Cheng-Ming Tsao, Shiu-Jen Chen, Shuk-Man Ka, Mei-Hui Liao, Chin-Chen Wu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2016-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:https://doi.org/10.1371/journal.pone.0150319
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