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Response to anaplastic lymphoma kinase inhibitor in gastric cancer harboring DCTN1–ALK fusion: a case report and review

Anaplastic lymphoma kinase (ALK) rearrangements are exceedingly rare in gastric cancer, and uncommon fusion types add to the difficulties of proper, precise treatment strategies. Although detected in non-small cell lung cancer (NSCLC), inflammatory myofibroblastic tumors (IMTs), and Spitz tumors, th...

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Principais autores: Huadi Wang, Liangkun You, Hong Pan, Xiaotong Qiu, Jin Sheng
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-10-01
Serier:Frontiers in Immunology
Fag:
anaplastic lymphoma kinase (ALK)
circulating tumor DNA (ctDNA)
next generation sequencing (NGS)
case report
review
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1686666/full
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