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More fit KL‐VS heterozygotes have more favorable AD‐relevant biomarker profiles

Abstract INTRODUCTION Although hallmarked by β‐amyloid plaques (Aβ) and neurofibrillary tangles (tau), Alzheimer's disease (AD) is a multifactorial disorder that involves neuroinflammation, neurodegeneration, and synaptic dysfunction. AD‐associated biomolecular changes seem to be attenuated in carri...

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Principais autores: Mackenzie Jarchow, Ira Driscoll, Brianne M. Breidenbach, Noah Cook, Catherine L. Gallagher, Sterling C. Johnson, Sanjay Asthana, Bruce P. Hermann, Mark A. Sager, Kaj Blennow, Henrik Zetterberg, Cynthia M. Carlsson, Gwendlyn Kollmorgen, Clara Quijano‐Rubio, Dane B. Cook, Dena B. Dubal, Ozioma C. Okonkwo
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2025-07-01
coleção:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
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Acesso em linha:https://doi.org/10.1002/trc2.70133
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