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Genome-scale CRISPR Cas9a knockout screen reveals genes that control glioblastoma susceptibility to the alkylating agent temozolomide

Glioblastoma is the most fatal of all primary human brain tumors, with a 14-month median survival. The mainstay therapy for this tumor involves temozolomide, surgery, radiotherapy, and tumor-treating electric field. Cancer resistance to commonly available chemotherapeutics remains a major challenge...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chidiebere U. Awah, Jan Winter, Olorunseun O. Ogunwobi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis Group 2022-12-01
Saila:All Life
Gaiak:
Sarrera elektronikoa:http://dx.doi.org/10.1080/26895293.2021.2024895
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