HNPCC <it>versus </it>sporadic microsatellite-unstable colon cancers follow different routes toward loss of HLA class I expression
<p>Abstract</p> <p>Background</p> <p>Abnormalities in Human Leukocyte Antigen (HLA) class I expression are common in colorectal cancer. Since HLA expression is required to activate tumor antigen-specific cytotoxic T-lymphocytes (CTL), HLA class I abnormalities represent a mechanism by which tumors c...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
BMC
2007-02-01
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| Edice: | BMC Cancer |
| On-line přístup: | http://www.biomedcentral.com/1471-2407/7/33 |
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